Leslie Charleson, the iconic actress best known for her decades-long role as Dr. Monica Quartermaine on ABC’s General Hospital, passed away at the age of 79. Her death, confirmed by her family, marks the end of a remarkable career that spanned over 50 years.
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Leslie Charleson’s portrayal of Dr. Monica Quartermaine on General Hospital began in 1977, a role that made her a household name. As part of the Quartermaine family, Leslie Charleson brought depth, complexity, and relatability to the character, making Monica one of the most beloved figures in daytime television. Her tenure on the show earned her multiple accolades and recognition from fans and peers alike.
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Throughout her time on General Hospital, Leslie Charleson was central to some of the show’s most memorable storylines, including intense family dramas, romantic entanglements, and groundbreaking medical cases. Her ability to balance the character’s professional life as a cardiologist with her tumultuous personal relationships endeared her to generations of viewers.
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Before joining General Hospital, Leslie Charleson built a successful career in television with appearances on Love Is a Many Splendored Thing and As the World Turns. Her talent and charisma quickly caught the attention of producers, setting the stage for her breakthrough role in the world of soap operas.
Following the news of her passing, tributes from co-stars, fans, and industry figures have flooded social media.
#GH RIP Leslie Charleson. I wonder who’s going to have the privilege of saying “it’s my house. Monica gave it to me.” pic.twitter.com/RckbLTujro
— Kevin No, Uh Really (@KevinNoahRiley2) January 13, 2025
Sad news, #GeneralHospital legend, @lesliecharleson has passed away. Brilliant actress but more importantly, one of the nicest in the business who always greeted anyone in her orbit with a big smile and open arms. The world will miss you, Leslie. RIP. 💔 https://t.co/bKXfVN0zsB pic.twitter.com/d7kTiV9iVk
— Nathan Varni (@nathanvarni) January 12, 2025
So so sad to hear about Leslie Charleson’s passing! Grew up watching Monica on screen and General Hospital will not be the same without her! Monica and Alan Quartermaine will always have a special place in my heart 💜😔 pic.twitter.com/nTMARgyhQO
— christina 🌻 #IStandWithKelly (@dellyandjasam) January 13, 2025
Sad Leslie has left us.
When I first began writing, #GH was one of the first shows I had pleasure to be involved with.
Alan & Monica were absolute royalty. & it all feels like yesterday.
RIP Leslie (also Stuart). You are an impossible act to follow or forget. #LeslieCharleson pic.twitter.com/ZLwnCOy3Ti
— John Larsen (@midnighter99) January 13, 2025
Leslie Charleson’s contributions to daytime television extend beyond her performances. She was a trailblazer for strong, complex female characters and a mentor to many young actors who joined General Hospital. Her dedication to the craft and her audience leaves an enduring legacy that will not be forgotten.
Details about memorial services have not yet been announced. In lieu of flowers, her family has requested donations to the American Heart Association, a cause closely tied to her role as a cardiologist on-screen.
Leslie Charleson’s passing is a profound loss to the entertainment world, but her remarkable body of work and the joy she brought to millions will live on. As fans and colleagues remember her, they celebrate a life and career defined by excellence, grace, and an unwavering commitment to her art.